CVN417

TargetMol Chemicals

CVN417

16

Chemical

Research Use Only

CVN417

CVN417 is an orally active antagonist of nAChR containing the alpha6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion. It inhibits Ca(2+) efflux through nAChR subunits, displaying IC50 values of 0.086 microM (alpha6), 2.56 microM (alpha3), and 0.657 microM (alpha4). CVN417 has shown efficacy in reducing resting tremor in rodent models, suggesting a potential to ameliorate movement disorders in conditions like Parkinsons disease [1].

3 years

-20°C

12352200