CVT-10216

MedChem Express

CVT-10216 [1005334-57-5]

10

1005334-57-5

Research Use Only

99.87

C24H19NO7S

465.48

CVT-10216 is a highly selective, reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC 50 of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC 50 of 1.3 microM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects [1] .

O=C(O)C1=CC=CC(COC2=CC=C3C(C(C4=CC=C(NS(=O)(C)=O)C=C4)=COC3=C2)=O)=C1

-20°C

12352200