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CXCR5 antibody [C1C2], Internal

Research Use Only
GTX100351
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCXCR5
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    CXCR5 antibody [C1C2], Internal
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID643
  • Target name
    CXCR5
  • Target description
    C-X-C motif chemokine receptor 5
  • Target synonyms
    BLR1; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; CD185; chemokine (C-X-C motif) receptor 5; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR15; MDR-15; monocyte-derived receptor 15
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene was identified as a gene specifically expressed in Burkitts lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice. Calvet-Mirabent M et al., 2022 Mar, Eur J Immunol
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  • CXC chemokine ligand-13 promotes metastasis via CXCR5-dependent signaling pathway in non-small cell lung cancer. Chao CC et al., 2021 Oct, J Cell Mol Med
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  • Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. Lin JR et al., 2018 Jul 11, Elife
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  • Frequency and distribution of CD4+CXCR5+ follicular B helper T cells within involved tissues in IgG4-related ophthalmic disease. Yang H et al., 2017 Dec, Mol Med Rep
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  • Proteomic analysis reveals a FANCA-modulated neddylation pathway involved in CXCR5 membrane targeting and cell mobility. Renaudin X et al., 2014 Aug 15, J Cell Sci
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