CXCR5 antibody [C1C2], Internal
GTX100351
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCXCR5
Overview
- SupplierGeneTex
- Product NameCXCR5 antibody [C1C2], Internal
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID643
- Target nameCXCR5
- Target descriptionC-X-C motif chemokine receptor 5
- Target synonymsBLR1; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; CD185; chemokine (C-X-C motif) receptor 5; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR15; MDR-15; monocyte-derived receptor 15
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene was identified as a gene specifically expressed in Burkitts lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice. Calvet-Mirabent M et al., 2022 Mar, Eur J ImmunolRead more
- CXC chemokine ligand-13 promotes metastasis via CXCR5-dependent signaling pathway in non-small cell lung cancer. Chao CC et al., 2021 Oct, J Cell Mol MedRead more
- Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. Lin JR et al., 2018 Jul 11, ElifeRead more
- Frequency and distribution of CD4+CXCR5+ follicular B helper T cells within involved tissues in IgG4-related ophthalmic disease. Yang H et al., 2017 Dec, Mol Med RepRead more
- Proteomic analysis reveals a FANCA-modulated neddylation pathway involved in CXCR5 membrane targeting and cell mobility. Renaudin X et al., 2014 Aug 15, J Cell SciRead more