Cyclin A2 Antibody / CCNA2
ORB606541
ApplicationsImmunoHistoChemistry
Product group Antibodies
Overview
- SupplierBiorbyt
- Product NameCyclin A2 Antibody / CCNA2
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT IHC-P
- CertificationResearch Use Only
- Clone IDCCNA2/2333
- IsotypeIgG
- Scientific DescriptionThis antibody recognizes a protein of 50-55 kDa, which is identified as Cyclin A. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, Cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while Cyclin B is a critical regulator of mitosis. Mutation or disruption of normal Cyclin A expression causes cells to arrest in G2-phase.
- UNSPSC12352203