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ProductsBack/cyclo(CLLFVY)

cyclo(CLLFVY)

HY-P10426

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
cyclo(CLLFVY)
Delivery Days Customer
5
Certification
Research Use Only
Scientific Description
cyclo(CLLFVY) is an inhibitor for hypoxia inducible factor-1 ( HIF-1 ), with IC 50 of 19 microM (in U2OS) and 16 microM (in MCF-7). cyclo(CLLFVY) binds to the PAS-B domain of HIF-1alpha, inhibits HIF-1 dimerization and transcriptional activity. cyclo(CLLFVY) downregulates the expression of hypoxia response genes, such as VEGF and CAIX, exhibits antitumor against the HIF-1 associated cancers [1] .
UNSPSC
12352202