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Cyclocreatine [35404-50-3]

Research Use Only
HY-W017540
MedChem Express
CAS Number35404-50-3
Product group Chemicals
Estimated Purity99.65
Molecular Weight143.15
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Cyclocreatine [35404-50-3]
  • Delivery Days Customer
    10
  • CAS Number
    35404-50-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C5H9N3O2
  • Molecular Weight
    143.15
  • Scientific Description
    Cyclocreatine, a creatine analogue, acts as a brain-penetrant and potent bioenergetic protective agent by providing high levels of ATP. Cyclocreatine can be phosphorylated and dephosphorylated by creatine kinases. Cyclocreatine suppresses creatine metabolism ameliorating the cognitive, autistic and epileptic phenotype in a mouse model of creatine transporter defciency. Cyclocreatine protects against ischemic injury and enhances cardiac recovery during early reperfusion in dogs and rats. Cyclocreatine decreases plaque-adjacent neuronal dystrophy in TREM2-deficient mice with amyloid-beta pathology. Cyclocreatine is proming for research of ischemic heart disease, cardiovascular diseases, Alzheimers disease and other neurodegenerative diseases associated with microglial dysfunction, prostate cancer[1][2][3][4][5].
  • SMILES
    O=C(O)CN1CCNC1=N
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200