CYM5442 (hydrochloride)
HY-10968A
CAS Number1783987-80-3
Product group Chemicals
Molecular Weight445.94
Overview
- SupplierMedChem Express
- Product NameCYM5442 (hydrochloride) [1783987-80-3]
- Delivery Days Customer10
- CAS Number1783987-80-3
- CertificationResearch Use Only
- Molecular FormulaC23H28ClN3O4
- Molecular Weight445.94
- Scientific DescriptionCYM5442 hydrochloride is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC 50 of 1.35 nM. CYM5442 hydrochloride is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 hydrochloride activates S1P1 -dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 hydrochloride can easily penetrate the central nervous system (CNS) [1] [2] .
- SMILESCCOC1=CC=C(C2=NC(C3=CC=CC4=C3CCC4NCCO)=NO2)C=C1OCC.[H]Cl
- UNSPSC12352200