Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CYP17A1 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CYP17A1 Polyclonal Antibody at dilution 1:30
CYP17A1 Polyclonal Antibody
E-AB-11124
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCYP17A1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.7mg/ml
- Scientific DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
- UNSPSC12352203