Western blot analysis of extracts from HUVEC cells, using Cytochrome P450 24A1 antibody.
Western blot analysis of extracts from HUVEC cells, using Cytochrome P450 24A1 antibody.
CYP24A1 Antibody
CSB-PA221533
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetCYP24A1
Overview
- SupplierCusabio
- Product NameCYP24A1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1591
- Target nameCYP24A1
- Target descriptioncytochrome P450 family 24 subfamily A member 1
- Target synonyms1,25-@dihydroxyvitamin D3 24-hydroxylase; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 24-OHase; CP24; CYP24; cytochrome P450 24A1; cytochrome P450, family 24, subfamily A, polypeptide 1; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); cytochrome P450-CC24; exo-mitochondrial protein; HCAI; HCINF1; P450-CC24; vitamin D 24-hydroxylase; vitamin D(3) 24-hydroxylase
- HostRabbit
- IsotypeIgG
- Protein IDQ07973
- Protein Name1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
- Scientific DescriptionHas a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product. Chen K.-S., Proc. Natl. Acad. Sci. U.S.A. 90:4543-4547(1993). Deloukas P., Nature 414:865-871(2001). Chen K.-S., Biochim. Biophys. Acta 1263:1-9(1995).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203