Cytokeratin 1 (Suprabasal Keratinocyte Marker)(KRT1/1840), 1mg/mL [26628-22-8]

Biotium

Cytokeratin 1 (Suprabasal Keratinocyte Marker)(KRT1/1840), 1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

KRT1/1840

1 mg/ml

KRT1

keratin 1

67 kDa cytokeratin; CK1; CK-1; cytokeratin 1; EHK; EHK1; epidermolytic hyperkeratosis 1; EPPK; hair alpha protein; K1; keratin 1, type II; keratin, type II cytoskeletal 1; KRT1A; NEPPK; type-II keratin Kb1

Mouse

IgG2a

Keratin, type II cytoskeletal 1

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Human, Mouse, Rat

-20°C

12352203