Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker)(KRT13/2213), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker)(KRT13/2213), CF405S conjugate, 0.1mg/mL

9

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

KRT13/2213

0.1 mg/ml

Other Conjugate

KRT13

keratin 13

CK13; CK-13; cytokeratin 13; K13; keratin 13, type I; keratin, type I cytoskeletal 13; WSN2

Mouse

IgG

Keratin, type I cytoskeletal 13

Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203