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Cytokeratin 14 (KRT14) (Squamous Cell Marker)(KRT14/2375), CF405S conjugate, 0.1mg/mL [26628-22-8]

Cytokeratin 14 (KRT14) (Squamous Cell Marker)(KRT14/2375), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC042375
Biotium
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Porcine, Rat
TargetKRT14
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Overview

  • Supplier
    Biotium
  • Product Name
    Cytokeratin 14 (KRT14) (Squamous Cell Marker)(KRT14/2375), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    KRT14/2375
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID3861
  • Target name
    KRT14
  • Target description
    keratin 14
  • Target synonyms
    CK14; cytokeratin 14; EBS3; EBS4; K14; keratin 14, type I; keratin, type I cytoskeletal 14; NFJ
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP02533
  • Protein Name
    Keratin, type I cytoskeletal 14
  • Scientific Description
    Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse, Porcine, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203