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Cytokeratin 8 antibody [N1C1]

GTX112975
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetKRT8
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cytokeratin 8 antibody [N1C1]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.12 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3856
  • Target name
    KRT8
  • Target description
    keratin 8
  • Target synonyms
    CARD2, CK-8, CK8, CYK8, K2C8, K8, KO, keratin, type II cytoskeletal 8, cytokeratin-8, keratin 8, type II, type-II keratin Kb8
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05787
  • Protein Name
    Keratin, type II cytoskeletal 8
  • Scientific Description
    This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kuo CH, Lin MW, Hsu YW, et al. Biomarker discovery in highly invasive lung cancer cell through proteomics approaches. Cell Biochem Funct. 2021,39(3):367-379. doi: 10.1002/cbf.3599
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  • Yu HI, Chou HC, Su YC, et al. Proteomic analysis of evodiamine-induced cytotoxicity in thyroid cancer cells. J Pharm Biomed Anal. 2018,160:344-350. doi: 10.1016/j.jpba.2018.08.008
    Read this paper
  • Li JM, Chou HC, Wang SH, et al. Hyaluronic acid-dependent protection against UVB-damaged human corneal cells. Environ Mol Mutagen. 2013,54(6):429-49. doi: 10.1002/em.21794
    Read this paper
  • Lu CH, Lin ST, Chou HC, et al. Proteomic analysis of retinopathy-related plasma biomarkers in diabetic patients. Arch Biochem Biophys. 2013,529(2):146-56. doi: 10.1016/j.abb.2012.11.004
    Read this paper
  • Cho CK, Smith CR, Diamandis EP. Amniotic fluid proteome analysis from Down syndrome pregnancies for biomarker discovery. J Proteome Res. 2010,9(7):3574-82. doi: 10.1021/pr100088k
    Read this paper