Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker)(AE-1), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker)(AE-1), CF405S conjugate, 0.1mg/mL

9

Research Use Only

Monoclonal

AE-1

0.1 mg/ml

Other Conjugate

KRT77

keratin 77

CK-1B; cytokeratin-1B; K1B; K77; keratin 1B; keratin 77, type II; keratin, type II cytoskeletal 1b; KRT1B; type-II keratin Kb39

Mouse

IgG1

Keratin, type II cytoskeletal 1b

This MAb recognizes the 56. 5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e. g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Canine, Chicken, Human, Monkey, Mouse, Rabbit, Reptile, Rat

2°C to 8°C

12352203