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Cytostatin (sodium salt)
T35613
CAS Number457070-06-3
Product group Chemicals
Molecular Weight451.452
Overview
- SupplierTargetMol Chemicals
- Product NameCytostatin (sodium salt)
- Delivery Days Customer44
- CAS Number457070-06-3
- Category SupplierChemical
- Chemical NameCytostatin (sodium salt)
- Molecular FormulaC21H33NaO7P
- Molecular Weight451.452
- Scientific DescriptionCytostatin (sodium salt) is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 ug/ml, respectively) and B16 cells metastatic activity in mice. It induces apoptosis of FS3 mouse fibrosarcoma cells (IC50 = 3.1 ug/ml). Cytostatin (sodium salt) potently and selectively inhibits protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5.
- Shelf life instruction3 years
- SMILES[Na].[H][C@]1(OC(=O)C=C[C@@H]1C)[C@@H](C)CC[C@H](OP(O)(O)=O)[C@@H](C)[C@@H](O)\C=C/C=C\C=C\C ;c:5;
- Storage Instruction-20°
- UNSPSC12352200