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CZC-25146

M6649
AbMole BioScience
CAS Number1191911-26-8
Product group Chemicals
Molecular Weight488.54
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    CZC-25146
  • Delivery Days Customer
    9
  • CAS Number
    1191911-26-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C22H25FN6O4S
  • Molecular Weight
    488.54
  • Scientific Description
    CZC 25146 is a potent and orally active LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well.
  • SMILES
    COC1=CC(=CC=C1NC2=NC=C(F)C(=N2)NC3=CC=CC=C3N[S](C)(=O)=O)N4CCOCC4
  • UNSPSC
    12352200

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