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CgoaEWY7Nr-EXi5sAAAAALyeHpk078.png
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CgoaEWY7Nr-EXi5sAAAAALyeHpk078.png

CZC-25146

T3053
TargetMol Chemicals
CAS Number1191911-26-8
Product group Chemicals
Molecular Weight488.54
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CZC-25146
  • Delivery Days Customer
    4
  • CAS Number
    1191911-26-8
  • Category Supplier
    Chemical
  • Chemical Name
    CZC-25146
  • Molecular Formula
    C22H25FN6O4S
  • Molecular Weight
    488.54
  • Scientific Description
    CZC-25146 (CHEMBL2397014) is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM for wild-type LRRK2(Leucine-rich repeat kinase-2) and G2019S LRRK2, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    O(C)C=1C=C(C=CC1NC=2N=C(NC3=C(NS(C)(=O)=O)C=CC=C3)C(F)=CN2)N4CCOCC4
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Ramsden N, et al. ACS Chem Biol. 2011 Oct 21;6(10):1021-8.
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