(D-Arg8)-Inotocin

MedChem Express

(D-Arg8)-Inotocin

14

Research Use Only

C39H68N14O11S2

973.17

(D-Arg8)-Inotocin is a potent, selective and competitive antagonist of vasopressin receptor (V1aR), with a Ki of 1.3 nM. (D-Arg8)-Inotocin shows more than 3000-fold selectivity for the human V1aR over the other three subtypes, OTR, V1bR and V2R[1].

O=C([C@H]1NC([C@@H](NC([C@](NC([C@](NC([C@@H](NC([C@H](CSSC1)N)=O)CC(C)C)=O)([H])[C@@H](C)CC)=O)([H])[C@H](O)C)=O)CC(N)=O)=O)N2[C@@H](CCC2)C(N[C@H](CCCNC(N)=N)C(NCC(N)=O)=O)=O

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