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ProductsBack/D-erythro-Dihydrosphingosine 1-phosphate [19794-97-9]
Chemical Structure
Chemical Structure
Chemical Structure

D-erythro-Dihydrosphingosine 1-phosphate [19794-97-9]

Research Use Only
AG-CR1-0005
AdipoGen Life Sciences
CAS Number19794-97-9
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight381.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    D-erythro-Dihydrosphingosine 1-phosphate [19794-97-9]
  • Delivery Days Customer
    10
  • CAS Number
    19794-97-9
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C18H40NO5P
  • Molecular Weight
    381.5
  • Scientific Description
    Chemical. CAS: 19794-97-9. Formula: C18H40NO5P. MW: 381.5. Saturated analog of sphingosine 1-phosphate (1-SP1). Ligand for sphingosine 1-phosphate (S1P/EDG) receptors. Negative control for intracellular effects of sphingosine 1-phosphate. Induces chemotaxis. Antifibrotic. - Saturated analog of sphingosine 1-phosphate (1-SP1). Ligand for sphingosine 1-phosphate (S1P/EDG) receptors [1,3]. Negative control for intracellular effects of sphingosine 1-phosphate [1]. Induces chemotaxis [2]. Antifibrotic [4].
  • SMILES
    CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)COP(O)(O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival: J.R. van Brocklyn, et al.; J. Cell Biol. 142, 229 (1998)
  • Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis: F. Wang, et al.; JBC 274, 35343 (1999)
  • Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218: J.R. van Brocklyn, et al. JBC 274, 4626 (1999)
  • Dihydrosphingosine 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels: Arthritis Rheum. 62, 2117 (2010)