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ProductsBack/DACH1 Antibody, Biotin conjugated

DACH1 Antibody, Biotin conjugated

Research Use Only
CSB-PA006482LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetDACH1
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Cusabio
  • Product Name
    DACH1 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID1602
  • Target name
    DACH1
  • Target description
    dachshund family transcription factor 1
  • Target synonyms
    dac homolog; DACH; dachshund homolog 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UI36
  • Protein Name
    Dachshund homolog 1
  • Scientific Description
    Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203