Dacomitinib Anhydrous [1110813-31-4]
D004098
Estimated Purity≥99%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameDacomitinib Anhydrous [1110813-31-4]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥99%
- FormatDMSO 75 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL
- Scientific DescriptionEGFR inhibitor.; PF00299804 Anhydrous
- Storage Instruction-20°C
- UNSPSC12352200
References
- Gonzales A., Hook K., Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor. Mol Cancer Ther. 7(7):1880-9 (2008). PMID: 18606718. Nagano T., Tachihara M., et al. Dacomitinib, a second-generation irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) to treat non-small cell lung cancer. Drugs Today (Barc). 55(4):231-236 (2019). PMID: 31050691. Momeny M., Esmaeili F., et al. The ERBB receptor inhibitor dacomitinib suppresses proliferation and invasion of pancreatic ductal adenocarcinoma cells. Cell Oncol. 2019. PMID: 31025257.