Dagrocorat (hydrochloride) [1044535-61-6]

MedChem Express

Dagrocorat (hydrochloride) [1044535-61-6]

10

1044535-61-6

Research Use Only

99.85

C29H30ClF3N2O2

531.01

Dagrocorat (PF-00251802) hydrochloride is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor. Dagrocorat hydrochloride is also a time-dependent reversible inhibitor of CYP3A (IC50=1.3 microM in human liver microsomes) and CYP2D6 (Ki=0.57 microM in human liver microsomes). Dagrocorat hydrochloride can be used for the research of rheumatoid arthritis[1].

O[C@@]1(C(F)(F)F)C[C@]2([H])[C@](C3=CC=C(C(NC(C=CC=N4)=C4C)=O)C=C3CC2)(CC1)CC5=CC=CC=C5.[H]Cl

-20°C,2°C to 8°C

12352200