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ProductsBack/DAMGO . AcOH [100929-53-1]
Chemical Structure
Chemical Structure
Chemical Structure

DAMGO . AcOH [100929-53-1]

Research Use Only
AG-CP3-0005V
AdipoGen Life Sciences
CAS Number100929-53-1
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight513.6 . 60.1
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    DAMGO . acetate [100929-53-1]
  • Delivery Days Customer
    10
  • CAS Number
    100929-53-1
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C26H35N5O6 . C2H4O2
  • Molecular Weight
    513.6 . 60.1
  • Scientific Description
    Chemical. CAS: 100929-53-1. Formula: C26H35N5O6 . C2H4O2. MW: 513.6 . 60.1. Synthetic. Potent, selective agonist of micro-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines and chemokine receptors through TGF-beta1. Increases food intake of rats. - Potent, selective agonist of micro-opioid receptor [1]. Antinociceptive [2,3]. Stimulates calcium-activated adenylyl cyclases related cAMP production [4]. Expresses chemokines and chemokine receptors through TGF-beta1 [5]. Increases food intake of rats [6].
  • SMILES
    O=C(NCCO)[C@@H](N(C(CNC([C@H](NC([C@@H]([NH3+])CC1=CC=C(O)C=C1)=O)C)=O)=O)C)CC2=CC=CC=C2.CC([O-])=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • DAMGO, a mu-opioid receptor selective agonist, distinguishes between mu- and delta-opioid receptors around their first extracellular loops: T. Onogi, et al.; FEBS Lett. 357, 93 (1995)
  • Galanin receptor antagonists attenuate spinal antinociceptive effects of DAMGO, tramadol and non-opioid drugs in rats: N. Selve, et al.; Brain Res. 735, 177 (1996)
  • Long-lasting antinociceptive effect of DAMGO chloromethyl ketone in rats: G. Szabo, et al.; Peptides 20, 1321 (1999)
  • The mu opioid agonist DAMGO stimulates cAMP production in SK-N-SH cells through a PLC-PKC-Ca++ pathway: V. Rubovitch, et al.; Mol. Brain Res. 110, 261 (2003)
  • DAMGO-induced expression of chemokines and chemokine receptors: the role of TGF-beta1: C. Happel, et al.; J. Leukoc. Biol. 83, 956 (2008)
  • Enkephalin surges in dorsal neostriatum as a signal eat: A.G. DiFeliceantonio, et al.; Curr. Biol. 22, 1918 (2012)