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Dapivirine [244767-67-7]

Research Use Only
D0261
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 293,00
5 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Dapivirine [244767-67-7]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    0.2mg/ml in DMSO and 0.3 mg/ml in DMF, sparingly soluble in aqueous buffers
  • Scientific Description
    RT inhibitor.; TMC120, R147681
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Devlin B, Nuttall J, Wilder S, et al. Development of dapivirine vaginal ring for HIV prevention. Antiviral Res. 2013 Dec;100 Suppl:S3-8. PMID: 24188702. Gupta SK, Nutan. Clinical use of vaginal or rectally applied microbicides in patients suffering from HIV/AIDS. HIV AIDS (Auckl). 2013 Oct 22;5:295-307. PMID: 24174883. Njai HF, Lewi PJ, Janssen CG, et al. Pre-incubation of cell-free HIV-1 group M isolates with non-nucleoside reverse transcriptase inhibitors blocks subsequent viral replication in co-cultures of dendritic cells and T cells. Antivir Ther. 2005;10(2):255-62. PMID: 15865220. Van Herrewege Y, Michiels J, Van Roey J, et al. In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides. Antimicrob Agents Chemother. 2004 Jan;48(1):337-9. PMID: 14693562.