Darbufelone (mesylate)

MedChem Express

Darbufelone (mesylate) [139340-56-0]

10

139340-56-0

Research Use Only

99.65

C19H28N2O5S2

428.57

Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF 2alpha and LTB 4 production. Darbufelone potently inhibits PGHS-2 ( IC 50 = 0.19 microM) but is much less potent with PGHS-1 ( IC 50 = 20 microM).

O=C1N=C(N)S/C1=C\C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2.CS(=O)(O)=O

2°C to 8°C

12352200