Dasatinib-d4

MedChem Express

Dasatinib-d4

5

Research Use Only

Dasatinib-d 4 (BMS-354825-d 4 ) is deuterium labeled Dasatinib. Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC 50 s of [1] [2] . Dasatinib also induces apoptosis and autophagy .

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