DB2313

MedChem Express

DB2313 [2170606-74-1]

10

2170606-74-1

Research Use Only

99.48

C42H41FN8O2

708.83

DB2313 is a potent inhibitor of transcription factor PU.1 . DB2313 inhibits PU.1 -dependent reporter gene transactivation with an IC 50 of 5 microM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects [1] .

FC1=C(COC2=CC=C(C3=NC4=CC=C(C(NC(C)C)=N)C=C4N3)C=C2)C=CC=C1COC5=CC=C(C6=NC7=CC=C(C(NC(C)C)=N)C=C7N6)C=C5

-20°C,2°C to 8°C

12352200