dBET57

AbMole BioScience

dBET57

9

1883863-52-2

Chemical

Research Use Only

C34H31ClN8O5S

699.18

dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2.

CC1=C(C)C2=C(S1)[N]3C(=NN=C3C(CC(=O)NCCNC4=CC=CC5=C4C(=O)N(C6CCC(=O)NC6=O)C5=O)N=C2C7=CC=C(Cl)C=C7)C

2-8°C, protect from light

12352200