dBET6 [1950634-92-0]

Biorbyt

dBET6 [1950634-92-0]

16

1950634-92-0

Research Use Only

C42H45CLN8O7S

841.3741

dBET6 is a highly potent, selective and cell-permeable degrader of BET with an IC50 of 14 nM, and has antitumor activity.

ClC1C([H])=C([H])C(=C([H])C=1[H])C1C2C(C([H])([H])[H])=C(C([H])([H])[H])SC=2N2C(C([H])([H])[H])=NN=C2[C@]([H])(C([H])([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(C([H])([H])OC2=C([H])C([H])=C([H])C3=C2C(N(C3=O)C2([H])C(N([H])C(C([H])([H])C2([H])[H])=O)=O)=O)=O)=O)N=1

12352200