
Western blot analysis of extracts from NIH-3T3 cells treated with H2O2 (100uM, 30mins) and COS-7 cells treated with PMA (125mg/ml, 30mins), using DBF4 antibody.
DBF4 Antibody
CSB-PA113425
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetDBF4
Overview
- SupplierCusabio
- Product NameDBF4 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10926
- Target nameDBF4
- Target descriptionDBF4 zinc finger
- Target synonymsactivator of S phase kinase; ASK; CHIF; chiffon homolog A; DBF4 homolog; DBF4 zinc finger A; DBF4A; DBF4-type zinc finger-containing protein 1; protein DBF4 homolog A; ZDBF1; zinc finger, DBF-type containing 1
- HostRabbit
- IsotypeIgG
- Protein IDQ9UBU7
- Protein NameProtein DBF4 homolog A
- Scientific DescriptionRegulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at Ser-40 and Ser-53 and then is involved in regulating the initiation of DNA replication during cell cycle. Kumagai H., Mol. Cell. Biol. 19:5083-5095(1999). Jiang W., EMBO J. 18:5703-5713(1999). Ota T., Nat. Genet. 36:40-45(2004).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203