DBF4 Antibody

Cusabio

DBF4 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at Ser-40 and Ser-53 and then is involved in regulating the initiation of DNA replication during cell cycle. Kumagai H., Mol. Cell. Biol. 19:5083-5095(1999). Jiang W., EMBO J. 18:5703-5713(1999). Ota T., Nat. Genet. 36:40-45(2004).

Human, Mouse

-20°C or -80°C

12352203