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DBPR112 [1226549-49-0]

DBPR112 [1226549-49-0]

T10965
TargetMol Chemicals
CAS Number1226549-49-0
DownloadMSDS
Product group Chemicals
Estimated Purity98.29%
Molecular Weight533.62
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    DBPR112 [1226549-49-0]
  • Delivery Days Customer
    9
  • CAS Number
    1226549-49-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    DBPR112
  • Estimated Purity
    98.29%
  • Molecular Formula
    C32H31N5O3
  • Molecular Weight
    533.62
  • Scientific Description
    DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM for EGFRWT and 48 nM for EGFRL858R/T790M, capable of occupying the ATP-binding site and demonstrating significant antitumor efficacy.
  • Shelf life instruction
    3 years
  • SMILES
    CN(C)C\C=C\C(=O)Nc1cccc(c1)-c1c(oc2ncnc(N[C@H](CO)c3ccccc3)c12)-c1ccccc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200