Bio-Connect

DBPR211

Research Use Only
ORB251373
Biorbyt
CAS Number1429239-98-4
Product group Chemicals
Molecular Weight750.12
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    DBPR211 [1429239-98-4]
  • Delivery Days Customer
    16
  • CAS Number
    1429239-98-4
  • Certification
    Research Use Only
  • Molecular Formula
    C33H31Cl2F3N6O3S2
  • Molecular Weight
    750.12
  • Scientific Description
    CB1-IN-1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0.3 nM (Ki, CB1R) 21 nM (Ki, CB2R) Target: CB1R in vivo: CB1-IN-1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice. CB1-IN-1 has great potential to ameliorate this related metabolic syndrome.
  • SMILES
    C1CCN(CC1)NC(=O)C2=NN(C(=C2CNS(=O)(=O)N3CCCC3)C4=CC=C(S4)C#CC5=CC=C(C=C5)C(F)(F)F)C6=C(C=C(C=C6)Cl)Cl
  • UNSPSC
    12352200