dBRD4-BD1 [2839318-19-1]

MedChem Express

dBRD4-BD1 [2839318-19-1]

5

2839318-19-1

Research Use Only

98.02

C50H53F3N8O9

967.00

dBRD4-BD1 is a selective and durable BRD4 degrader with an DC50 value of 280 nM (Dmax=77%). dBRD4-BD1 upregulates BRD2/3 protein level and shows low cytotoxicity than iBRD4-BD1[1].

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(OCC(NCCOCCOCCN4CCC(CC4)N5C=NC(C6=CC=C(C(F)(F)F)C=C6)=C5C7=CC=NC(OC8=CC(C(C)C)=CC=C8C)=N7)=O)=CC=C3)=O)=O

-20°C,2°C to 8°C

12131703