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dBRD9 HCl [2341840-98-8]

dBRD9 HCl [2341840-98-8]

T31221L
TargetMol Chemicals
Estimated Purity99.37%
Product group Chemicals
Molecular Weight856.75
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    dBRD9 HCl [2341840-98-8]
  • Delivery Days Customer
    16
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    dBRD9 HCl
  • Estimated Purity
    99.37%
  • Molecular Formula
    C40H47Cl2N7O10
  • Molecular Weight
    856.75
  • Scientific Description
    dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). dBRD9 HCl does not degrade BRD4 or BRD7 at concentrations up to 5 microM. dBRD9 HCl displays antiproliferative effects in human AML cell lines.
  • Shelf life instruction
    3 years
  • SMILES
    O=C1C2=C(C(C3=CC(OC)=C(CN(CC(NCCOCCOCCNC4=CC=CC(C(N5C6C(NC(CC6)=O)=O)=O)=C4C5=O)=O)C)C(OC)=C3)=CN1C)C=CN=C2.Cl.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200