DC0-NH2 [615538-51-7]

TargetMol Chemicals

DC0-NH2 [615538-51-7]

72

615538-51-7

Chemical

Research Use Only

DC0-NH2

C31H24ClN5O3

550.01

The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then adenine residue is alkylated by its propabenzindole (CBI) component.

3 years

Nc1ccc2[nH]c(cc2c1)C(=O)Nc1ccc2[nH]c(cc2c1)C(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21

-20°C

12352200