dCas9 C-terminal Cloning Vector

Applied Biological Materials

dCas9 C-terminal Cloning Vector

9

Other Application

Research Use Only

This Cas9 Double Mutant (dCas9) has changes at amino acid positions D10A and H840A which completely inactivate both the nuclease and nickase activities. With a target-specific guide RNA (sgRNA), it can bind to a specific region of DNA without cutting it. This vector provides an in-frame downstream multiple cloning site, allowing users to attach any protein of interest to the C-terminus of dCas9. The resulting construct will also carry a C-terminal nuclear localization signal.

-20°C

41106600