DCLK1-IN-5 [3028774-14-0]

TargetMol Chemicals

DCLK1-IN-5 [3028774-14-0]

16

Research Use Only

C26H32ClN7O3S2

590.16

DCLK1-IN-5 (Compound a24), with an IC 50 of 179.7 nM, acts as a DCLK1 inhibitor. It mitigates lipopolysaccharide-induced inflammation by blocking DCLK1-mediated IKKbeta phosphorylation. Additionally, DCLK1-IN-5 offers protection to mice from lung injuries and sepsis caused by inflammation [1].

S(C(C)C)(=O)(=O)C1=C(NC2=NC(NC3=C(OC)C=C(NC(=S)N4CCN(C)CC4)C=C3)=NC=C2Cl)C=CC=C1

-20°C

51202000