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ProductsBack/DCLX069 [792946-69-1]
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DCLX069 [792946-69-1]

Research Use Only
T27133
TargetMol Chemicals
CAS Number792946-69-1
DownloadMSDS
Product group Chemicals
Molecular Weight339.43
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    DCLX069 [792946-69-1]
  • Delivery Days Customer
    4
  • CAS Number
    792946-69-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    DCLX069
  • Molecular Formula
    C20H25N3O2
  • Molecular Weight
    339.43
  • Scientific Description
    DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17.9 microM, occupying the SAM binding pocket to exert its inhibitory effect. It effectively blocks cell proliferation in breast cancer, liver cancer, and acute myeloid leukemia cell lines.
  • Shelf life instruction
    3 years
  • SMILES
    CCOC(=O)C1=CC(N)=C(C=C1)N1CCN(CC2=CC=CC=C2)CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Yiqian Xie, et al. Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1). Org Biomol Chem. 2014 Dec 21;12(47):9665-73.
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