Decanoyl-RVKR-CMK
78713-3
CAS Number150113-99-8
Product group Chemicals
Estimated Purity≥95%
Molecular Weight744.42
Overview
- SupplierBPS Bioscience
- Product NameDecanoyl-RVKR-CMK
- Delivery Days Customer7
- CAS Number150113-99-8
- CertificationResearch Use Only
- Estimated Purity≥95%
- Format500 microg (#78713-1) or 1 mg (#78713-2) or 5 mg (#78713-3)
- Molecular FormulaC34H66ClN11O5
- Molecular Weight744.42
- Scientific DescriptionDecanoyl-Arg-Val-Lys-Arg-chlororomethylketone, also called Subtilisin/Kex2p-like proprotein convertase inhibitor, is a small, synthetic, irreversible and cell-permeable modified RVKR peptide that inhibits the seven pro-protein convertases: furin and PC1, PC2, PC4, PACE4, PC5, PC7. Proprotein convertases cleave proproteins to generate bioactive peptides or to activate enzymes and growth factors, thus regulating critical biological processes and playing a role in pathologies such as cancer or viral infection. Therefore, they represent potential therapeutic targets in a number of diseases. As an inhibitor of furin, Decanoyl-RVKR-CMK blocks the fusion of flavaviruses and coronaviruses, including SARS-CoV-2, with the membrane of human host cells. It also inhibits the processing of
- Storage Instruction-20°C
- UNSPSC12352200