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Decanoyl-RVKR-CMK

Research Use Only
78713-3
BPS Bioscience
CAS Number150113-99-8
Product group Chemicals
Estimated Purity≥95%
Molecular Weight744.42
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Packing Size
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Decanoyl-RVKR-CMK
  • Delivery Days Customer
    7
  • CAS Number
    150113-99-8
  • Certification
    Research Use Only
  • Estimated Purity
    ≥95%
  • Format
    500 microg (#78713-1) or 1 mg (#78713-2) or 5 mg (#78713-3)
  • Molecular Formula
    C34H66ClN11O5
  • Molecular Weight
    744.42
  • Scientific Description
    Decanoyl-Arg-Val-Lys-Arg-chlororomethylketone, also called Subtilisin/Kex2p-like proprotein convertase inhibitor, is a small, synthetic, irreversible and cell-permeable modified RVKR peptide that inhibits the seven pro-protein convertases: furin and PC1, PC2, PC4, PACE4, PC5, PC7. Proprotein convertases cleave proproteins to generate bioactive peptides or to activate enzymes and growth factors, thus regulating critical biological processes and playing a role in pathologies such as cancer or viral infection. Therefore, they represent potential therapeutic targets in a number of diseases. As an inhibitor of furin, Decanoyl-RVKR-CMK blocks the fusion of flavaviruses and coronaviruses, including SARS-CoV-2, with the membrane of human host cells. It also inhibits the processing of
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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