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ProductsBack/Decernotinib [944842-54-0]

Decernotinib [944842-54-0]

Research Use Only
D364086
LKT Laboratories
Estimated Purity≥99%
Product group Chemicals
€ 1.130,00
100 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Decernotinib [944842-54-0]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥99%
  • Format
    DMSO
  • Scientific Description
    JAK3 inhibitor.; VX-509, VRT-831509, Adelitinib
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Farmer L., Ledeboer M., et al. Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. J Med Chem. 58(18):7195-216 (2015). PMID: 26230873. Elwood F., Witter D., et al. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor. 361(2):229-44 (2017). PMID:28193636. Genovese M., van Vollenhoven R., et al. VX-509 (Decernotinib), an Oral Selective JAK-3 Inhibitor, in Combination With Methotrexate in Patients With Rheumatoid Arthritis. Arthritis Rheumatol. 68(1):46-55 (2016). PMID: 26473751.