Decernotinib (VX-509,adelatinib)

Biorbyt

Decernotinib (VX-509,adelatinib) [944842-54-0]

16

944842-54-0

Research Use Only

C18H19F3N6O

392.3783

Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.

FC(C([H])([H])N([H])C([C@@](C([H])([H])[H])(C([H])([H])C([H])([H])[H])N([H])C1C([H])=C([H])N=C(C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=N3)N=1)=O)(F)F

12352200