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Dehydrobruceine B [53730-90-8]

Dehydrobruceine B [53730-90-8]

T75485
TargetMol Chemicals
Molecular Weight478.45
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Dehydrobruceine B [53730-90-8]
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Dehydrobruceine B
  • Molecular Formula
    C23H26O11
  • Molecular Weight
    478.45
  • Scientific Description
    Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing factor (AIF) and Bax while inhibiting Keap1-Nrf2 [1].
  • Shelf life instruction
    3 years
  • SMILES
    C(OC)(=O)[C@]12[C@]3([C@]4([C@@]([C@]5(C)C(C[C@]4(OC(=O)[C@@H]3OC(C)=O)[H])=C(C)C(=O)C(O)=C5)([C@@H](O)[C@@H]1O)[H])CO2)[H]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200