DEL-22379

MedChem Express

DEL-22379 [181223-80-3]

10

181223-80-3

Research Use Only

99.69

C26H28N4O3

444.53

DEL-22379 is an ERK dimerization Inhibitor. DEL-22379 readily binds to ERK2 with a Kd estimated in the low micromolar range, though binding is detectable even at low nanomolar concentrations. ERK2 dimerization is progressively inhibited with an IC50 of ~0.5 microM.

O=C(CCN1CCCCC1)NC2=CC=C(NC(/C3=C\C4=CNC5=C4C=C(OC)C=C5)=O)C3=C2

-20°C,2°C to 8°C

12352200