Demethoxycurcumin [24939-17-1]

Sheu MJ, Lin HY, Yang YH, et al. Demethoxycurcumin, a major active curcuminoid from Curcuma longa, suppresses balloon injury induced vascular smooth muscle cell migration and neointima formation: an in vitro and in vivo study. Mol Nutr Food Res. 2013 Sep;57(9):1586-97. PMID: 23520190. Shieh JM, Chen YC, Lin YC, et al. Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells. J Agric Food Chem. 2013 Jul 3;61(26):6366-75. PMID: 23777448. Villaflores OB, Chen YJ, Chen CP, et al. Curcuminoids and resveratrol as anti-Alzheimer agents. Taiwan J Obstet Gynecol. 2012 Dec;51(4):515-25. PMID: 23276553. Hung CM, Su YH, Lin HY, et al. Demethoxycurcumin Modulates Prostate Cancer Cell Proliferation via AMPK-Induced Down-regulation of HSP70 and EGFR. J Agric Food Chem. 2012 Aug 16. PMID: 22849866. Ni X, Zhang A, Zhao Z, et al. Demethoxycurcumin inhibits cell proliferation, migration and invasion in prostate cancer cells. Oncol Rep. 2012 Jul;28(1):85-90. PMID: 22552297. Zhang L, Wu C, Zhao S, et al. Demethoxycurcumin, a natural derivative of curcumin attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-kappaB signaling pathways in N9 microglia induced by lipopolysaccharide. Int Immunopharmacol. 2010 Mar;10(3):331-8. PMID: 20018257. Ahmed T, Gilani AH. Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease. Pharmacol Biochem Behav. 2009 Feb;91(4):554-9. PMID: 18930076. Agrawal DK, Saikia D, Tiwari R, et al. Demethoxycurcumin and its semisynthetic analogues as antitubercular agents. Planta Med. 2008 Dec;74(15):1828-31. PMID: 18991209.