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ProductsBack/Demethylnobiletin

Demethylnobiletin

Research Use Only

S9421

Product group Chemicals

Overview

Supplier
Selleck Chemicals
Product Name
Demethylnobiletin
Delivery Days Customer
9
Certification
Research Use Only
Scientific Description
Demethylnobiletin (5-Demethylnobiletin) is a unique flavonoid found in citrus fruits with potential chemopreventive effects against human cancers.5-Demethylnobiletin is a direct inhibitor of 5-LOX with IC50 of 0.1 muM, without affecting the expression of COX-2. 5-Demethylnobiletin has anti-inflammatory activity, inhibits leukotriene B 4(LTB4) formation in rat neutrophils and elastase release in human neutrophils with IC50 of 0.35 muM.
UNSPSC
12352200