WB analysis of HeLa cell lysate using GTX04326 DEPDC5 antibody. The lane on the right was treated with blocking peptide.
WB analysis of HeLa cell lysate using GTX04326 DEPDC5 antibody. The lane on the right was treated with blocking peptide.
DEPDC5 antibody
GTX04326
Overview
- SupplierGeneTex
- Product NameDEPDC5 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9681
- Target nameDEPDC5
- Target descriptionDEP domain containing 5, GATOR1 subcomplex subunit
- Target synonymsDEP domain-containing protein 5; DEP.5; FFEVF; FFEVF1; GATOR complex protein DEPDC5
- HostRabbit
- IsotypeIgG
- Protein IDO75140
- Protein NameGATOR complex protein DEPDC5
- Scientific DescriptionThis gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203