DEPDC5 (phospho Ser1002) antibody

GeneTex

DEPDC5 (phospho Ser1002) antibody

9

WB: 1:1000-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

DEPDC5

DEP domain containing 5, GATOR1 subcomplex subunit

DEP domain-containing protein 5; DEP.5; FFEVF; FFEVF1; GATOR complex protein DEPDC5

Rabbit

IgG

GATOR complex protein DEPDC5

This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203