Dersimelagon

MedChem Express

Dersimelagon [1835256-48-8]

10

1835256-48-8

Research Use Only

98.66

C36H45F4N3O5

675.75

Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor ( MC1R ) agonist with EC 50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with K i values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation [1] [2] .

O=C(N1C[C@H](C2=C(N3CCC(C(O)=O)CC3)C=C(C(F)(F)F)C=C2)[C@@H](COC)C1)[C@]4([C@H](C5=CC=C(OC)C=C5)CN(C6CCCC6)C4)F

-20°C

12352200