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Deruxtecan [1599440-13-7]

Research Use Only
T15098
TargetMol Chemicals
CAS Number1599440-13-7
DownloadMSDS
Product group Chemicals
Molecular Weight1034.05
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Deruxtecan [1599440-13-7]
  • Delivery Days Customer
    9
  • CAS Number
    1599440-13-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Deruxtecan
  • Molecular Formula
    C52H56FN9O13
  • Molecular Weight
    1034.05
  • Scientific Description
    Deruxtecan is an ADC drug-linker conjugate comprising a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used in synthesizing DS-8201 and U3-1402.
  • Shelf life instruction
    3 years
  • SMILES
    CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)COCNC(=O)CNC(=O)[C@H](Cc6ccccc6)NC(=O)CNC(=O)CNC(=O)CCCCCN6C(=O)C=CC6=O)c(c3Cn1c2=O)c45
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
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