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ProductsBack/Deshydroxy LY-411575 [209984-56-5]

Deshydroxy LY-411575 [209984-56-5]

Research Use Only
D1773
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 179,00
5 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Deshydroxy LY-411575 [209984-56-5]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    DMSO 95 mg/mL (198.13 mM); Ethanol 13 mg/mL (27.11 mM); Water Insoluble
  • Scientific Description
    gamma-Secretase inhibitor.; YO-01027, Dibenzazepine analog, Iminostilbene analog, gamma-Secretase Inhibitor XX, DBZ, GSI-XX
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Petersen N, Reimann F, van Es JH, et al. Targeting development of incretin-producing cells increases insulin secretion. J Clin Invest. 2015 Jan;125(1):379-85. PMID: 25500886. Xiao Z, Zhang J, Peng X, et al. The Notch gamma-secretase inhibitor ameliorates kidney fibrosis via inhibition of TGF-bèta/Smad2/3 signaling pathway activation. Int J Biochem Cell Biol. 2014 Oct;55:65-71. PMID: 25150830. Zheng YH, Li FD, Tian C, et al. Notch gamma-secretase inhibitor dibenzazepine attenuates angiotensin II-induced abdominal aortic aneurysm in ApoE knockout mice by multiple mechanisms. PLoS One. 2013 Dec 16;8(12):e83310. PMID: 24358274.